This depends on the size of your project, your goals and needs.
For more complex projects, I design primarily on Webflow so that I have unlimited design capabilities - unlike DIY website builders like Squarespace and Wix, it has endless customisation capabilities for truly unique websites.
Webflow also has a great client editor functionality - so you won't need to hire me or other web developers in the future if you want to make simple content updates, which is generally the case if you opt for Wordpress. This saves you a whole lot of stress and money in the long run.
If the primary purpose of your website, however, is to open an online store, then I recommend Shopify. In this case I will design your website and work with a developer so we can give it a unique finish.